Nm23 (Nme/NDPK/Awd) gene/protein family consists of ten members originally named after the first one identified, Nm23-H1/NDPK A, which is considered to be a metastasis suppressor gene

Besides their basic function in maintenance of the cellular NTP pool, the Nm23 proteins have several additional biochemical activities responsible for different cellular events leading, in consequence, to their involvement in major human diseases, especially cancer and cardiovascular diseases. During the last twenty years researchers working in this field meet triennially at the International Congress of the NDPK/Nm23/awd Family.

The intention is to gather all the groups and scientists interested in any of the vast number of subjects connected to NDPK/Nm23/Awd gene/protein family to recapitulate and discuss the main breakthroughs in the field.

This year we will celebrate the 10th anniversary of our conferences.

The conference is organized by Ruđer Bošković Institute, Zagreb, and sponsored by International Centre for Genetic Engineering and Biotechnology (ICGEB).

Specific focus will be put on the following topics:


  • gen/protein structure and evolution
  • involvement in development of various species
  • interaction with specific proteins and signalling pathways
  • involvement in physiology and related diseases
  • involvement in cancer and metastasis formation
  • potential use in cancer diagnostics, prognostics and therapy
  • mammalian histidine kinases


Organizing Committee

  • Maja Herak Bosnar, Rudjer Bošković Institute, Croatia, chair
  • Ana Vidoš, Rudjer Bošković Institute, Croatia, Conference and Marketing Coordinator
  • Martina Deželjin, Hannover Medical School, Germany
  • Helena Ćetković, Rudjer Bošković Institute, Croatia
  • Nikolina Hanžić, Rudjer Bošković Institute, Croatia
  • Neda Slade, Rudjer Bošković Institute, Croatia

Scientific Committee

  • Maja Herak Bosnar, Rudjer Bošković Institute, Croatia
  • Tien Hsu, Boston University School of Medicine, USA
  • Anil Mehta, University of Dundee, UK
  • Erle Robertson, University of Pennsylvania Medical School, USA
  • Patricia Steeg, National Cancer Institute, USA
  • Thomas Wieland, University of Heidelberg, Germany
  • Massimo Zollo, CEINGE, Italy

Important Dates

  • Abstract submission site open: May 9th
  • Registration site open: May 9th
  • Early abstract submission and registration deadline: July 8th
  • Abstract submission deadline: August 1st
  • Notification of accepted abstracts: August 5th
  • Registration and payment deadline: August 15th
  • Preliminary program available online: September 1st

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